Description

(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-Octahydroisoquinoline is a chiral, non-racemic organic compound featuring a complex, saturated isoquinoline scaffold substituted with a 4-methoxybenzyl group at the nitrogen position. This compound matters as a sophisticated pharmaceutical intermediate and chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring high stereochemical purity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents, particularly those targeting the central nervous system (CNS).
• Chiral Ligand or Catalyst Synthesis: Used to construct complex, enantiopure ligands for asymmetric catalysis.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides or herbicides.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a probe molecule in biological assays.
• Process Chemistry Development: Used for scaling up synthetic routes to chiral compounds under Good Manufacturing Practice (GMP) conditions.
• Academic & Industrial R&D: A valuable compound for methodological research in organic synthesis and stereochemistry.

Basic Information

Product Name	(S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-Octahydroisoquinoline
CAS No.	30356-07-1
Molecular Formula	C17H23NO
Molecular Weight	257.37 g/mol
Synonyms	(S)-1-[(4-Methoxyphenyl)methyl]-1,2,3,4,5,6,7,8-octahydroisoquinoline; (S)-1-(p-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline; (S)-1-(4-Methoxybenzyl)octahydroisoquinoline; (S)-1-PMB-octahydroisoquinoline; (S)-PMB-OHIQ; (S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-tetrahydroisoquinoline (common misnomer); (S)-N-(4-Methoxybenzyl)decahydroisoquinoline (related name); (S)-enantiomer of 1-(4-Methoxybenzyl)octahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-Octahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with customer specifications and high-purity standards. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.