Description

Oxitropium Bromide is a quaternary ammonium anticholinergic agent primarily used as a bronchodilator. This compound is of significant interest in the pharmaceutical industry for the development and production of inhalation therapies targeting respiratory conditions. It is essential for manufacturers and R&D facilities focused on creating treatments for chronic obstructive pulmonary disease (COPD) and asthma.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in metered-dose inhalers (MDIs) and dry powder inhalers (DPIs) for respiratory diseases.
• Respiratory Drug Formulations: Used in the development and commercial production of long-acting muscarinic antagonist (LAMA) therapies.
• Clinical Research & Development: Serves as a reference standard and key intermediate in preclinical and clinical studies for new respiratory drugs.
• Generic Drug Manufacturing: Critical for companies producing generic versions of established bronchodilator medications.
• Analytical Testing: Employed as a high-purity standard in HPLC and other analytical methods for quality control and regulatory testing.

Basic Information

Product Name	Oxitropium Bromide
CAS No.	30286-75-0
Molecular Formula	C19H26BrNO4 • H2O
Molecular Weight	430.33 g/mol (monohydrate)
Synonyms	Oxitropium Bromide Monohydrate; Ba 253 BR; Oxitropium Bromide (USAN); (1R,2R,4S,5S,7s)-9-Ethyl-7-[(hydroxydi-2-thienylacetyl)oxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide; Ba-253; Oxitropium Bromide Hydrate; Oxitropii Bromidum; TL 309
EINECS	Contact for details

Quality Control

Our Oxitropium Bromide is manufactured under strict quality management systems. It is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with pharmacopeial requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure regulatory compliance and supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.