Description

4-Iodo-2,5-Dimethylthiophene-3-Carbaldehyde is a high-purity, functionalized heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand Synthesis: The aldehyde and iodine functional groups make it valuable for constructing complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine substituent is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl and conjugated systems.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent probes or affinity tags for studying biological processes.

Basic Information

Product Name	4-Iodo-2,5-Dimethylthiophene-3-Carbaldehyde
CAS No.	30187-32-7
Molecular Formula	C7H7IOS
Molecular Weight	266.10 g/mol
Synonyms	3-Formyl-4-iodo-2,5-dimethylthiophene; 2,5-Dimethyl-4-iodothiophene-3-carboxaldehyde; 4-Iodo-2,5-dimethyl-3-thiophenecarboxaldehyde; 4-Iodo-2,5-dimethylthiophene-3-carboxaldehyde; 3-Thiophenecarboxaldehyde, 4-iodo-2,5-dimethyl-; 2,5-Dimethyl-4-iodo-3-thiophenecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Iodo-2,5-Dimethylthiophene-3-Carbaldehyde undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.