Description

(2S)-2-Hydroxy-3-Mercapto-Propanoic Acid is a chiral organic compound featuring both hydroxyl and thiol functional groups, making it a versatile building block for asymmetric synthesis. This high-purity intermediate is critical for applications requiring precise stereochemistry and controlled reactivity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of certain ACE inhibitors, anti-cancer agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral herbicides and fungicides, where the specific stereochemistry can influence biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing thiol-dependent biochemical pathways.
• Peptide & Protein Modification: The thiol group allows for site-specific conjugation, labeling, or cross-linking of biomolecules.
• Catalyst & Ligand Preparation: Acts as a starting material for synthesizing chiral ligands used in asymmetric catalysis for fine chemical production.
• Cosmetic & Personal Care Ingredients: Potential intermediate for synthesizing antioxidants or skin-conditioning agents.

Basic Information

Product Name	(2S)-2-Hydroxy-3-Mercapto-Propanoic Acid
CAS No.	30163-03-2
Molecular Formula	C3H6O3S
Molecular Weight	122.14 g/mol
Synonyms	(S)-2-Hydroxy-3-mercaptopropanoic acid; L-2-Hydroxy-3-mercaptopropionic acid; (S)-Thiolactic acid; (2S)-2-Hydroxy-3-sulfanylpropanoic acid; 3-Mercapto-L-lactic acid; L-3-Mercaptolactic acid; (S)-3-Mercaptolactic acid; 2-Hydroxy-3-mercaptopropionic acid (L-form)
EINECS	Contact for details

Quality Control

Our (2S)-2-Hydroxy-3-Mercapto-Propanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets stringent specifications for research and GMP-grade applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.