Description

4,5-Dibromo-3-Methylthiophene-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki coupling reactions and the synthesis of thiophene-based polymers or active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its brominated thiophene core for bioactivity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of two bromine atoms, enabling the construction of complex biaryl systems.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	4,5-Dibromo-3-Methylthiophene-2-Carbaldehyde
CAS No.	30153-49-2
Molecular Formula	C6H4Br2OS
Molecular Weight	283.97 g/mol
Synonyms	3-Methyl-4,5-dibromothiophene-2-carboxaldehyde; 4,5-Dibromo-3-methyl-2-thiophenecarboxaldehyde; 2-Formyl-4,5-dibromo-3-methylthiophene; 4,5-Dibromo-3-methylthiophene-2-carboxaldehyde; 3-Methyl-4,5-dibromothiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4,5-Dibromo-3-Methylthiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.