Description

4,5α-Epoxy-3-Methoxy-17-Methylmorphinan is a key morphinan-based intermediate with significant pharmaceutical relevance. Its defined stereochemistry and functional groups make it a critical precursor in the synthesis of more complex active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent opioid analgesics and related therapeutic agents.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and the development of new chemical entities targeting the central nervous system.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and process optimization for the commercial manufacturing of specialty APIs.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions and metabolic pathways.

Basic Information

Item	Detail
Product Name	4,5α-Epoxy-3-Methoxy-17-Methylmorphinan
CAS No.	3990-01-0
Molecular Formula	C₁₉H₂₅NO₂
Molecular Weight	299.41 g/mol
Synonyms	3-Methoxy-17-methyl-4,5α-epoxymorphinan; 4,5α-Epoxy-3-methoxy-17-methylmorphinan; 17-Methyl-4,5α-epoxy-3-methoxymorphinan; Thebaine derivative intermediate; Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5α)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,5α-Epoxy-3-Methoxy-17-Methylmorphinan is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.