Description

Thiophosphoryl Chloride is a key organophosphorus reagent with the CAS number 3982-91-0. It serves as a versatile building block for introducing the thiophosphoryl (P=S) moiety into target molecules, enabling the synthesis of a wide range of valuable compounds. This high-purity intermediate is essential for manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to develop advanced products.

Application

• Agrochemical Synthesis: A critical intermediate for manufacturing organothiophosphate insecticides, herbicides, and fungicides.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs containing phosphorus-sulfur bonds.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal catalysis and coordination chemistry.
• Flame Retardant Production: Employed in the manufacture of certain phosphorus-based flame retardant additives for polymers and materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in novel organophosphorus chemistry.
• Lubricant and Oil Additives: Used in the production of extreme pressure (EP) and anti-wear additives.

Basic Information

Product Name	Thiophosphoryl Chloride
CAS No.	3982-91-0
Molecular Formula	PSCl3
Molecular Weight	169.40 g/mol
Synonyms	Phosphorothioic Trichloride; Phosphorus Sulfochloride; Thiophosphoryl Trichloride; Phosphorothioic Chloride; P=SCl3; Thiophosphoric Acid Trichloride; Phosphorus Thiochloride; Thiophosphoric Chloride
EINECS	223-622-6

Quality Control

Our Thiophosphoryl Chloride is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including assay by titration and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and water. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature: 2°C to 8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Density (at 20°C)	1.63 - 1.67 g/mL
Boiling Point	124 - 126 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.