Description

4-Bromo-1(2H)-Isoquinolone is a halogenated isoquinoline derivative, a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its bromine substituent, which provides a reactive handle for further functionalization via cross-coupling and substitution reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting neurological disorders, cancer, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for creating specialized polymers, ligands, and organic electronic materials.
• Academic & R&D: Essential for methodological studies in organic synthesis, including palladium-catalyzed cross-coupling (e.g., Suzuki, Heck reactions) and nucleophilic aromatic substitution.
• Ligand Synthesis: Used to prepare novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-1(2H)-Isoquinolone
CAS No.	3951-95-9
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	4-Bromoisoquinolin-1(2H)-one; 4-Bromo-2H-isoquinolin-1-one; 4-Bromo-1-isoquinolinol; 4-Bromo-1-hydroxyisoquinoline; 1(2H)-Isoquinolone, 4-bromo-; 4-Bromoisocarbostyril
EINECS	Contact for details

Quality Control

Our 4-Bromo-1(2H)-Isoquinolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.