Description

1-Acetyl-5-Ethylidene-2-[3-(2-Hydroxyethyl)-1H-Indol-2-Yl]-α-Methylene-4-Piperidineacetic Acid Methyl Ester is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical synthesis. Its intricate molecular architecture, featuring fused indole and piperidine moieties, makes it a valuable building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules in GMP or non-GMP settings.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological assays due to its functional groups.

Basic Information

Product Name	1-Acetyl-5-Ethylidene-2-[3-(2-Hydroxyethyl)-1H-Indol-2-Yl]-α-Methylene-4-Piperidineacetic Acid Methyl Ester
CAS No.	3909-65-7
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Methyl 1-acetyl-5-ethylidene-2-[3-(2-hydroxyethyl)-1H-indol-2-yl]-α-methylenepiperidine-4-acetate; 4-Piperidineacetic acid, 1-acetyl-5-ethylidene-2-[3-(2-hydroxyethyl)-1H-indol-2-yl]-α-methylene-, methyl ester; 3909-65-7; 1-Acetyl-5-ethylidene-2-[3-(2-hydroxyethyl)-1H-indol-2-yl]-α-methylenepiperidine-4-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Ethylidene-2-[3-(2-Hydroxyethyl)-1H-Indol-2-Yl]-α-Methylene-4-Piperidineacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.