Description

4-(Aminosulfonyl)-5-Chlorophthalimide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, incorporating both a reactive phthalimide moiety and a sulfonamide group, which makes it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes where the sulfonamide group can act as a bioisostere.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its chlorinated aromatic system.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized colorants and functional dyes due to its conjugated aromatic framework.
• Polymer Modification: Employed to introduce sulfonamide functional groups into polymer chains, altering properties like solubility, thermal stability, or biological activity.
• Chemical Research & Development: A valuable reagent for academic and industrial research focused on heterocyclic chemistry, medicinal chemistry, and material science.
• Ligand Synthesis for Catalysis: Potential starting material for creating novel ligands used in metal-catalyzed reactions.

Basic Information

Product Name	4-(Aminosulfonyl)-5-Chlorophthalimide
CAS No.	3861-99-2
Molecular Formula	C8H5ClN2O4S
Molecular Weight	260.65 g/mol
Synonyms	5-Chloro-4-sulfamoylphthalimide; 4-Sulfamoyl-5-chlorophthalimide; 5-Chloro-4-sulfamoyl-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 5-chloro-4-(aminosulfonyl)-; NSC 403796; 5-Chlorophthalimide-4-sulfonamide
EINECS	223-386-8

Quality Control

Our 4-(Aminosulfonyl)-5-Chlorophthalimide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.