Description

2,5-Dimethoxybenzyl Chloride is a versatile and reactive benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual methoxy substitution pattern, which directs reactivity and enables the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the dimethoxybenzyl moiety is a core structural element.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Intermediate in the synthesis of advanced organic dyes and pigments, contributing to color fastness and specific spectral properties.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing material properties like adhesion, solubility, or reactivity.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new synthetic routes and novel compounds.

Basic Information

Product Name	2,5-Dimethoxybenzyl Chloride
CAS No.	3840-27-5
Molecular Formula	C9H11ClO2
Molecular Weight	186.64 g/mol
Synonyms	1-(Chloromethyl)-2,5-dimethoxybenzene; 2,5-Dimethoxybenzyl Chloride; 2,5-Dimethoxy-α-chlorotoluene; (2,5-Dimethoxyphenyl)methyl Chloride; α-Chloro-2,5-dimethoxytoluene; Benzene, 1-(chloromethyl)-2,5-dimethoxy-; 2,5-Dimethoxybenzylchloride
EINECS	223-340-7

Quality Control

Our 2,5-Dimethoxybenzyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.