Description

Diethyl 4-Methylbenzylphosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective formation of carbon-carbon double bonds. This makes it an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing styryl or substituted alkene moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific alkene structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing phosphonate-based ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the creation of novel monomers and polymers with tailored properties via olefination chemistry.
• Flavor and Fragrance Industry: Intermediate for the synthesis of specific aroma chemicals and fragrance compounds.
• Organic Synthesis Reagent: A reliable reagent in academic and industrial R&D labs for constructing complex organic molecules through HWE reactions.

Basic Information

Product Name	Diethyl 4-Methylbenzylphosphonate
CAS No.	3762-25-2
Molecular Formula	C₁₂H₁₉O₃P
Molecular Weight	242.25 g/mol
Synonyms	Diethyl (4-methylbenzyl)phosphonate; (4-Methylbenzyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[(4-Methylphenyl)methyl]-, Diethyl Ester; Diethyl p-Tolylmethylphosphonate; Diethyl (p-Methylbenzyl)phosphonate; Diethyl 4-Methylbenzyl Phosphonate; NSC 163082
EINECS	223-183-5

Quality Control

Every batch of Diethyl 4-Methylbenzylphosphonate is produced and tested under a stringent quality management system to ensure consistency and reliability for your synthetic processes. We provide comprehensive analytical data, including purity by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for each shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.5080 - 1.5120
Density (20°C)	1.080 - 1.100 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.