Description

Dimethylchlorophosphite is a versatile organophosphorus reagent primarily used as a key intermediate in chemical synthesis. Its value lies in its reactivity as a chlorinating and phosphorylating agent, enabling the construction of complex phosphorus-containing molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the production of advanced intermediates, ligands, and flame retardants.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for creating active pharmaceutical ingredients (APIs), particularly those containing phosphorus heterocycles or phosphate ester prodrugs.
• Agrochemical Production: Used in the manufacture of organophosphate insecticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing phosphite and phosphonite ligands used in asymmetric catalysis and transition metal complexes.
• Flame Retardant Formulation: An intermediate in the production of phosphorus-based flame retardant additives for polymers and plastics.
• Chemical Research & Development: Employed in organic synthesis laboratories for the introduction of dimethylphosphinyl or chlorophosphinyl groups.
• Polymer Modification: Used to modify polymer chains or create functional monomers with specific phosphorus properties.

Basic Information

Product Name	Dimethylchlorophosphite
CAS No.	3743-07-5
Molecular Formula	C2H6ClO2P
Molecular Weight	128.49 g/mol
Synonyms	Chlorodimethoxyphosphine; Dimethyl Phosphorochloridite; Phosphorochloridic Acid, Dimethyl Ester; Dimethoxyphosphinous Chloride; P,P-Dimethyl Phosphorochloridite; NSC 84466; Chlorophosphonic Acid Dimethyl Ester
EINECS	223-136-5

Quality Control

Our Dimethylchlorophosphite is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.20 g/cm³
Refractive Index (n20D)	~1.435

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.