Description

2-Methoxy-[1,3,2]-Dioxaphospholane is a versatile organophosphorus compound, specifically a cyclic phosphite ester, that serves as a crucial building block and reagent in advanced chemical synthesis. Its primary value lies in its reactivity as a phosphorylating agent and its role as a precursor for modifying biomolecules and polymers. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to introduce phosphonate or phosphate functionalities under controlled conditions.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of nucleotide analogs, prodrugs, and other bioactive molecules requiring phosphate or phosphonate groups.
• Polymer Modification: Used as a monomer or cross-linking agent in the production of specialty polymers, including flame retardants and functional materials.
• Ligand Synthesis: Serves as a precursor for creating novel phosphite and phosphonite ligands used in asymmetric catalysis and coordination chemistry.
• Surface Functionalization: Employed to phosphorylate surfaces or nanomaterials to alter their biocompatibility, hydrophilicity, or binding properties.
• Agrochemical Research: Intermediate in the development of new herbicides, insecticides, and plant growth regulators with phosphorous-based activity.
• Chemical Biology Tool: Utilized for labeling or modifying proteins, sugars, and other biomolecules to study biological processes.

Basic Information

Product Name	2-Methoxy-[1,3,2]-Dioxaphospholane
CAS No.	3741-36-4
Molecular Formula	C₃H₇O₃P
Molecular Weight	122.06 g/mol
Synonyms	2-Methoxy-1,3,2-dioxaphospholane; 2-Methoxy-2-oxo-1,3,2-dioxaphospholane; Methyl Ethylene Phosphate; Methyl Ethylene Phosphite; 2-Methoxy-1,3,2-dioxaphospholane 2-oxide; Cyclic Methyl Ethylene Phosphate; Phospholane, 2-methoxy-1,3,2-dioxa-
EINECS	223-128-7

Quality Control

Every batch of 2-Methoxy-[1,3,2]-Dioxaphospholane is produced and tested under stringent quality management protocols to ensure consistency and purity for critical research and production applications. Our products undergo rigorous quality testing, including chromatographic analysis and spectroscopic identification, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.