Description

(1H-Imidazol-2-Yl)-Methanol is a versatile heterocyclic building block characterized by its imidazole core functionalized with a hydroxymethyl group. This compound is of significant commercial interest as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), catalysts, and specialty polymers who require a reliable supply of high-purity intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including antifungal agents, kinase inhibitors, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators that leverage the imidazole moiety for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating N,O-bidentate ligands used in transition metal catalysis for organic transformations.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for synthesizing specialty polymers, such as polybenzimidazoles, with applications in high-temperature and conductive materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Coordination Chemistry: Used to prepare metal-organic frameworks (MOFs) or complexes due to its ability to coordinate with various metal ions.

Basic Information

Product Name	(1H-Imidazol-2-Yl)-Methanol
CAS No.	3724-26-3
Molecular Formula	C4H6N2O
Molecular Weight	98.10 g/mol
Synonyms	2-(Hydroxymethyl)imidazole; 2-Imidazolemethanol; 1H-Imidazole-2-methanol; 2-Hydroxymethylimidazole; (Imidazol-2-yl)methanol; 2-Imidazolylmethanol; α-Hydroxymethylimidazole; NSC 403697
EINECS	223-076-9

Quality Control

Our (1H-Imidazol-2-Yl)-Methanol is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.