Description

Malonic Acid, [2-14C] is a carbon-14 labeled isotopologue of malonic acid, a fundamental dicarboxylic acid. This radiolabeled compound is essential for tracing metabolic pathways and studying reaction mechanisms in research and development. It is a critical tool for scientists in pharmaceutical development, agrochemical research, and biochemistry, enabling precise tracking of carbon atoms in complex biological and chemical systems.

Application

• Tracer Studies in Metabolism: Used to elucidate biosynthetic pathways and metabolic fate in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) studies for new drug candidates.
• Agrochemical Research: Employed in the development and environmental fate studies of herbicides, pesticides, and plant growth regulators to understand degradation and metabolite formation.
• Biochemical Synthesis: Serves as a labeled building block for the synthesis of more complex radiolabeled compounds, including pharmaceuticals, vitamins, and fine chemicals.
• Mechanistic Organic Chemistry: Aids in investigating reaction mechanisms, such as Knoevenagel condensations, where the labeled carbon allows for precise tracking of bond formation and cleavage.
• Environmental Science: Applied in studies monitoring the biodegradation of chemicals and pollutants in soil and water systems.

Basic Information

Product Name	Malonic Acid, [2-14C]
CAS No.	3715-08-0
Molecular Formula	C14CH4O4 / C3H4O4 (¹⁴C labeled)
Molecular Weight	106.05 g/mol (nominal for unlabeled); Specific activity provided on COA.
Synonyms	Propanedioic-2-¹⁴C Acid; [2-¹⁴C]Malonic Acid; ¹⁴C-Labeled Malonic Acid; Carboxyacetic-2-¹⁴C Acid; Dicarboxymethane-2-¹⁴C; Methanedicarboxylic-2-¹⁴C Acid; Radiolabeled Malonate; Carbon-14 Malonic Acid
EINECS	Contact for details

Quality Control

Every batch of Malonic Acid, [2-14C] is produced and analyzed under strict quality systems to ensure radiochemical purity, chemical purity, and specific activity meet exacting standards for research use. Comprehensive Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and radio-TLC analyses. Our quality commitment ensures reliable, reproducible data for your critical tracer studies.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, keep the primary container within a secondary sealed container in a designated, well-ventilated area for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (Radio-TLC/HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solubility	Soluble in water, alcohols, pyridine

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.