Description

1,1,2-Trimethylpropylborane is a versatile organoborane compound with significant utility in advanced organic synthesis. Its primary value lies in its role as a key reagent for the introduction of the bulky 1,1,2-trimethylpropyl (neopentyl-like) group and in cross-coupling reactions. This chemical is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures. Its application extends to materials science for the development of novel boron-containing polymers and precursors.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal boron reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds and complex intermediates.
• Pharmaceutical Intermediate Synthesis: Used to incorporate sterically hindered alkyl groups into active pharmaceutical ingredients (APIs) and key building blocks.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific boron-functionalized structures.
• Materials Science & Polymer Chemistry: Serves as a monomer or functionalization agent in the creation of boron-doped polymers and specialty materials.
• Organic Synthesis Reagent: Utilized in hydroboration reactions and as a precursor for other organoboron derivatives.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel boron-based catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	1,1,2-Trimethylpropylborane
CAS No.	3688-24-2
Molecular Formula	C6H15B
Molecular Weight	98.00 g/mol
Synonyms	Neopentylborane; (1,1,2-Trimethylpropyl)borane; Tri-tert-butylborane (common misnomer); 1,1,2-Trimethylpropylboron; B-(1,1,2-Trimethylpropyl)borane; 2,2-Dimethylbutylborane; Borane, (1,1,2-trimethylpropyl)-
EINECS	Contact for details

Quality Control

Our 1,1,2-Trimethylpropylborane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area at 2-8°C due to its highly volatile and easily oxidized nature. Keep away from heat, sparks, open flames, and strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.