Description

4-(4-Amino-Phenyl)-Thiazol-2-Ylamine is a high-purity organic intermediate featuring a unique molecular structure combining an aromatic amine with a thiazole ring. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and specialty chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides due to its bioactive thiazole core.
• Material Science Research: Serves as a monomer or functional unit in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Industry: Employed as an intermediate for synthesizing specialized dyes and organic pigments, leveraging its conjugated amine-thiazole system.
• Biochemical Research: Utilized as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	4-(4-Amino-Phenyl)-Thiazol-2-Ylamine
CAS No.	3673-53-8
Molecular Formula	C9H9N3S
Molecular Weight	191.25 g/mol
Synonyms	2-Amino-4-(4-aminophenyl)thiazole; 4-(2-Aminothiazol-4-yl)aniline; 2,4-Diamino-4'-thiazolylbiphenyl; 4-(4-Aminophenyl)-2-aminothiazole; 4-(2-Amino-1,3-thiazol-4-yl)benzenamine; 2-Amino-4-(p-aminophenyl)thiazole; NSC 403697; p-(2-Aminothiazol-4-yl)aniline
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-Phenyl)-Thiazol-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.