Description

n-Methylacetamide-D7 is a deuterated analog of N-methylacetamide, where seven hydrogen atoms are replaced with deuterium. This high isotopic purity compound is essential for advanced analytical and research applications where precise molecular tracking and minimal background interference are required. It serves as a critical internal standard, solvent, or reagent in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and pharmaceutical research for studying reaction mechanisms and metabolic pathways.

Application

• NMR Spectroscopy Solvent & Internal Standard: Used as a deuterated solvent or quantitative internal standard for high-resolution NMR analysis in organic chemistry and structural biology.
• Mass Spectrometry (MS): Employed as a stable isotope-labeled internal standard for accurate quantification in LC-MS and GC-MS methods, particularly in proteomics and metabolomics.
• Pharmaceutical Research & Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies by tracing labeled compounds in biological systems.
• Chemical Reaction Mechanism Studies: Acts as a deuterium-labeled probe to investigate reaction pathways, kinetics, and isotope effects in synthetic chemistry.
• Analytical Reference Material: Serves as a certified reference material (CRM) for calibrating instruments and validating analytical methods in quality control laboratories.
• Polymer & Material Science Research: Used in studies involving deuterated polymers or as a solvent for characterizing material properties via spectroscopic techniques.

Basic Information

Product Name	n-Methylacetamide-D7
CAS No.	3669-74-7
Molecular Formula	C3D7NO
Molecular Weight	90.14 g/mol
Synonyms	N-Methylacetamide-d7; N-Methyl-d3-acetamide-d4; Acetamide, N-methyl-d7-; Deuterated N-Methylacetamide; Perdeuterated N-Methylacetamide; [2H7]-N-Methylacetamide; N-(Methyl-d3)acetamide-d4; NMR Solvent NMA-d7
EINECS	Contact for details

Quality Control

Our n-Methylacetamide-D7 is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes rigorous analysis using advanced techniques including NMR, MS, and HPLC to verify deuterium enrichment and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D atom %), chemical purity, and specific tests is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.