Description

n-Methyl-D3-Acetamide-2,2,2-D3 is a deuterated isotopologue of N-methylacetamide, a compound of significant interest in analytical and synthetic chemistry. Its core value lies in its utility as a stable, non-radioactive isotopic tracer and an internal standard for mass spectrometry, ensuring precise and reliable quantitative analysis. This product is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors, where it is used to study metabolic pathways, reaction mechanisms, and to ensure analytical method accuracy.

Application

• As a deuterated internal standard for the accurate quantification of N-methylacetamide and related compounds via LC-MS or GC-MS.
• In metabolic studies and pharmacokinetics as a stable isotopic tracer to track drug metabolism and distribution.
• For NMR spectroscopy as a solvent or chemical shift reference, leveraging its distinct deuterium signature.
• In organic synthesis as a building block for introducing deuterium labels into more complex molecules for mechanistic studies.
• Within material science research to investigate hydrogen-deuterium exchange phenomena and molecular interactions.
• For analytical method development and validation in regulatory environments requiring high-precision measurements.

Basic Information

Product Name	n-Methyl-D3-Acetamide-2,2,2-D3
CAS No.	3669-73-6
Molecular Formula	C3D6NO
Molecular Weight	78.12 g/mol
Synonyms	N-Methylacetamide-d6; Deuterated N-Methylacetamide; N-Methyl-d3-acetamide-2,2,2-d3; Acetamide-d6, N-methyl-; (2H6)-N-Methylacetamide; N-(Methyl-d3)acetamide-2,2,2-d3; N-Methylacetamide-d3 (methyl-d3); Perdeuterated N-Methylacetamide
EINECS	Contact for details

Quality Control

Our n-Methyl-D3-Acetamide-2,2,2-D3 is produced under strict quality management protocols to ensure exceptional isotopic and chemical purity. Each batch is characterized by advanced analytical techniques including NMR, MS, and HPLC to confirm deuterium enrichment and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical assay, and solvent residues is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.