Description

n-Methylacetamide-2,2,2-D3 is a deuterated isotopologue of N-methylacetamide, where the three methyl protons of the acetamide moiety are replaced by deuterium atoms. This labeled compound is essential for advanced research and analytical applications where tracking molecular behavior or eliminating background signals is critical. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a solvent for NMR spectroscopy, and a building block in mechanistic and metabolic studies.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for nuclear magnetic resonance (NMR) analysis, providing a non-interfering signal for high-resolution structural elucidation of organic compounds.
• Internal Standard for Mass Spectrometry: Serves as a precise internal standard in quantitative LC-MS and GC-MS methods, particularly in proteomics, metabolomics, and pharmacokinetic studies.
• Mechanistic Reaction Studies: Employed as a labeled reagent to investigate reaction mechanisms, pathways, and kinetics in synthetic organic chemistry and catalysis research.
• Metabolic Tracing: Acts as a stable isotope-labeled tracer in biomedical and environmental research to study metabolic pathways and degradation processes.
• Pharmaceutical Intermediate: Utilized in the synthesis of deuterated drug candidates, where the incorporation of deuterium can improve metabolic stability and pharmacokinetic profiles.
• Polymer Science Research: Applied in studies of polymer dynamics, solvent interactions, and as a model compound for understanding hydrogen bonding and solvation effects.

Basic Information

Product Name	n-Methylacetamide-2,2,2-D3
CAS No.	3669-69-0
Molecular Formula	C3H4D3NO
Molecular Weight	76.11 g/mol
Synonyms	N-Methylacetamide-d3; Acetamide-d3, N-methyl-; N-Methyl-d3-acetamide; (2,2,2-Trideuterio-N-methylacetamide); N-Methylacetamide (methyl-d3); Deuterated N-Methylacetamide; CD3C(O)N(H)CH3; N-Methylacetamide-2,2,2-trideuterio
EINECS	Contact for details

Quality Control

Our n-Methylacetamide-2,2,2-D3 is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity, and impurity profile. We adhere to rigorous quality testing protocols to guarantee consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.