Description

1,2,3,4,5,6-Hexahydro-8-Hydroxy-6,11-Dimethyl-2,6-Methano-3-Benzazocine-3-Acetonitrile is a complex, high-purity organic compound with a unique bridged-ring structure, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) and analgesic drug discovery pipelines. This product is essential for R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel opioid receptor ligands and other CNS-active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities for pain management.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and complex molecular transformations.
• Preclinical Development: Supports the production of compounds for pharmacological screening and toxicology studies.

Basic Information

Product Name	1,2,3,4,5,6-Hexahydro-8-Hydroxy-6,11-Dimethyl-2,6-Methano-3-Benzazocine-3-Acetonitrile
CAS No.	3639-69-8
Molecular Formula	C₁₉H₂₄N₂O₂
Molecular Weight	312.41 g/mol
Synonyms	8-Hydroxy-6,11-dimethyl-2,6-methano-3-benzazocine-3-acetonitrile, 1,2,3,4,5,6-hexahydro-; 3-Cyano-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine; 8-Hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-3-acetonitrile; 1,2,3,4,5,6-Hexahydro-8-hydroxy-6,11-dimethyl-2,6-methano-3-benzazocine-3-acetonitrile; 8-Hydroxy-6,11-dimethyl-2,6-methano-3-benzazocine-3-acetonitrile (hexahydro derivative); A bridged benzazocine nitrile derivative.
EINECS	Contact for details

Quality Control

Our 1,2,3,4,5,6-Hexahydro-8-Hydroxy-6,11-Dimethyl-2,6-Methano-3-Benzazocine-3-Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.