Description

2-Chloro-6-Methanesulfonyl-Benzothiazole is a high-value, multi-functional heterocyclic building block and key intermediate in advanced organic synthesis. Its unique structure, featuring both a chloro and a methanesulfonyl substituent on the benzothiazole core, makes it a versatile precursor for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiazole scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes, fluorescent markers, and photographic sensitizers.
• Cross-Coupling Reactions: The chloro group is an excellent site for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig), enabling rapid diversification of molecular structures.
• Sulfonyl Group Manipulation: The methanesulfonyl moiety can be further modified or reduced, providing a handle for introducing sulfur-containing functional groups.

Basic Information

Product Name	2-Chloro-6-Methanesulfonyl-Benzothiazole
CAS No.	3622-29-5
Molecular Formula	C8H6ClNO2S2
Molecular Weight	247.72 g/mol
Synonyms	2-Chloro-6-(methylsulfonyl)benzothiazole; 6-(Methylsulfonyl)-2-chlorobenzothiazole; 2-Chloro-6-methanesulphonylbenzothiazole; Benzothiazole, 2-chloro-6-(methylsulfonyl)-; 2-Chloro-6-methylsulfonylbenzothiazole; 2-Chloro-6-(methanesulfonyl)benzothiazole; 3622-29-5; 2-Chloro-6-mesylbenzothiazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methanesulfonyl-Benzothiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.