Description

4,5-Dichloro-2-Trifluoromethylbenzimidazole is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and fluorinated structure. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern imparts critical electronic and steric properties. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted biological activity and material performance.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel benzimidazole-based drugs, including potential antiviral, antimicrobial, and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing custom fine chemicals for client-specific projects.

Basic Information

Product Name	4,5-Dichloro-2-Trifluoromethylbenzimidazole
CAS No.	3615-21-2
Molecular Formula	C8H3Cl2F3N2
Molecular Weight	255.02 g/mol
Synonyms	2-(Trifluoromethyl)-4,5-dichloro-1H-benzimidazole; 4,5-Dichloro-2-(trifluoromethyl)-1H-benzimidazole; 1H-Benzimidazole, 4,5-dichloro-2-(trifluoromethyl)-; 4,5-Dichloro-2-trifluoromethyl-1H-benzimidazole; 3615-21-2; 4,5-Dichloro-2-(trifluoromethyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2-Trifluoromethylbenzimidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.