Description

Methyl Diphenylphosphite is a versatile organophosphorus compound widely used as a key intermediate and ligand in advanced chemical synthesis. Its primary value lies in its ability to act as a phosphitylating agent and a precursor for more complex phosphorus-containing molecules, which are essential in various high-value manufacturing processes. This product is particularly critical for industries involved in pharmaceuticals, agrochemicals, and specialty polymer production, where precise chemical functionality is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phosphorus-based functional groups or prodrug strategies.
• Agrochemical Synthesis: Serves as a key building block for manufacturing certain classes of pesticides, herbicides, and plant growth regulators.
• Ligand in Catalysis: Employed as a precursor for chiral or achiral phosphite ligands used in homogeneous catalysis, including hydrogenation and hydroformylation reactions.
• Polymer Additive & Stabilizer: Functions as an intermediate in the production of phosphite-based antioxidants and stabilizers for plastics and polymers.
• Flame Retardant Precursor: Utilized in the development of organophosphorus flame retardants for engineering plastics and textiles.
• Organic Synthesis Reagent: Acts as a phosphitylating agent in nucleotide chemistry and for the protection of alcohols in multi-step synthetic routes.

Basic Information

Product Name	Methyl Diphenylphosphite
CAS No.	3577-87-5
Molecular Formula	C13H13O3P
Molecular Weight	248.21 g/mol
Synonyms	Diphenyl Methylphosphite; Methyl Diphenyl Phosphite; Diphenyl Methoxyphosphonite; Methoxy(diphenoxy)phosphine; P-Methoxy-P,P-diphenylphosphinous acid; Phosphorous acid, methyl diphenyl ester; NSC 404122
EINECS	222-685-9

Quality Control

Our Methyl Diphenylphosphite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.555 - 1.565
Density (20°C)	1.18 - 1.22 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.