Description

(+)-Cyclazocine CAS NO 3572-80-3 is a high-purity, enantiomerically pure benzomorphan derivative with significant pharmacological activity. This compound is a critical reference standard and research chemical for investigating opioid receptor systems, particularly the κ-opioid receptor (KOR). It is essential for pharmaceutical R&D, analytical laboratories, and academic institutions focused on neuroscience, pain management, and addiction research.

Application

• Pharmacological Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in pharmaceutical testing.
• Neuroscience Research: A vital tool for studying the function and modulation of κ-opioid receptors (KOR) in the central nervous system.
• Drug Discovery & Development: Serves as a key intermediate or active comparator in the synthesis and screening of novel analgesic and neuropsychiatric agents.
• Metabolic Studies: Employed in in vitro and in vivo studies to understand the metabolic pathways and pharmacokinetics of benzomorphan analogs.
• Academic & Clinical Research: Supports fundamental research into pain mechanisms, substance use disorders, and receptor pharmacology.

Basic Information

Product Name	(+)-Cyclazocine
CAS No.	3572-80-3
Molecular Formula	C18H25NO
Molecular Weight	271.40 g/mol
Synonyms	(+)-Cyclazocine; Win 29,424; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; (5R,9R,13S)-6,11-Dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methanobenzazocin-8-ol; (+)-trans-Cyclazocine; NSC 107429
EINECS	Contact for details

Quality Control

Our (+)-Cyclazocine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and purity meet exacting standards for research use. A detailed Certificate of Analysis (COA) providing HPLC/GC purity, chiral assay, and related substance data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.