Description

2-Methyl-5-Nitro-1H-Indole-3-Carbaldehyde is a versatile nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an aldehyde and a nitro group on the indole scaffold, makes it a valuable building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive indole core.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, condensations, and cyclizations to create complex molecular architectures.
• Material Science: Serves as a monomer or precursor for functional dyes, pigments, and organic electronic materials.
• Academic & R&D: A standard reagent in university and industrial research laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	2-Methyl-5-Nitro-1H-Indole-3-Carbaldehyde
CAS No.	3558-17-6
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	5-Nitro-2-methyl-1H-indole-3-carboxaldehyde; 2-Methyl-5-nitroindole-3-carboxaldehyde; 3-Formyl-2-methyl-5-nitroindole; 1H-Indole-3-carboxaldehyde, 2-methyl-5-nitro-; 5-Nitro-2-methylindole-3-carbaldehyde; 2-Methyl-5-nitro-1H-indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Nitro-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.