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11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(3-Cyclopentylpropionate) CAS NO 3545-59-3


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CAS No.:3545-59-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(3-Cyclopentylpropionate) is a high-purity synthetic corticosteroid derivative, specifically a prodrug of methylprednisolone. This compound is valued for its potent anti-inflammatory and immunosuppressive activity, offering a critical building block for advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry for the development and production of specialized steroid-based therapeutics.

Application

  • Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacture of corticosteroid medications.
  • Pharmaceutical Research & Development: Used in preclinical and clinical research for studying glucocorticoid receptor activity and developing new anti-inflammatory drugs.
  • Prodrug Synthesis: Serves as a prodrug form of methylprednisolone, designed for modified release profiles or improved bioavailability.
  • Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
  • Biochemical Research: Utilized in studies investigating the mechanisms of steroid hormone action, immune response modulation, and metabolic pathways.

Basic Information

Product Name 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(3-Cyclopentylpropionate)
CAS No. 3545-59-3
Molecular Formula C30H42O6
Molecular Weight 498.65 g/mol
Synonyms Methylprednisolone 21-Cyclopentanepropionate; Methylprednisolone Cyclopentylpropionate; 6α-Methylprednisolone 21-Cyclopentylpropionate; U-67590A; 6α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-cyclopentylpropionate; Medrol Cyclopentylpropionate; 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-(3-cyclopentylpropanoate)
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Quality Control

Our 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(3-Cyclopentylpropionate) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediates and research chemicals. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time corresponds to reference standard
Assay (HPLC) ≥98.0%
Related Substances (HPLC) Total impurities ≤2.0% Any single impurity ≤1.0%
Loss on Drying ≤1.0%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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