Description

2-Bromo-7-Nitrobenzothiazole is a versatile and high-value heterocyclic building block, primarily recognized for its role as a key intermediate in advanced organic synthesis. Its molecular structure, featuring both bromo and nitro substituents on the benzothiazole core, makes it a critical precursor for constructing complex molecules with tailored electronic and biological properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its reactive sites for structural diversification.
• Dye and Pigment Manufacturing: Acts as a building block for synthesizing specialized dyes, optical brighteners, and pigments due to the nitrobenzothiazole chromophore.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and photoactive materials for electronic applications.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags and molecular probes for diagnostic and research purposes.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination.

Basic Information

Product Name	2-Bromo-7-Nitrobenzothiazole
CAS No.	3507-49-1
Molecular Formula	C7H3BrN2O2S
Molecular Weight	259.08 g/mol
Synonyms	7-Nitro-2-bromobenzothiazole; 2-Bromo-7-nitro-1,3-benzothiazole; Benzothiazole, 2-bromo-7-nitro-; 2-Brom-7-nitrobenzothiazol; 2-Bromo-7-nitrobenzo[d]thiazole
EINECS	Contact for details

Quality Control

Our 2-Bromo-7-Nitrobenzothiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and potential reactivity with strong oxidizing agents, ensure proper segregation in storage areas. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.