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1-Bromopyrrolidine-2,5-Dione CAS NO 3493-39-8
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CAS No.:3493-39-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Bromopyrrolidine-2,5-Dione is a versatile and highly reactive brominating agent, specifically an N-bromoimide. Its core value proposition lies in its ability to perform selective bromination reactions under mild conditions, making it a crucial reagent for introducing bromine atoms into complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and efficient bromination for synthesizing active ingredients, intermediates, and advanced materials.
Application
- Pharmaceutical Intermediate Synthesis: Key reagent for the bromination of active pharmaceutical ingredients (APIs) and their precursors, particularly in the synthesis of antiviral and anticancer compounds.
- Agrochemical Production: Used in the manufacture of brominated herbicides, fungicides, and pesticides, where selective bromination enhances biological activity.
- Organic Synthesis & Research: A fundamental tool in academic and industrial R&D labs for electrophilic bromination, allylic bromination, and benzylic bromination reactions.
- Polymer & Material Science: Employed to modify polymers and create brominated monomers for flame-retardant materials and specialty polymers.
- Fine Chemical Manufacturing: Facilitates the production of complex brominated aromatics and heterocycles used as dyes, pigments, and photographic chemicals.
Basic Information
| Product Name | 1-Bromopyrrolidine-2,5-Dione |
| CAS No. | 3493-39-8 |
| Molecular Formula | C₄H₄BrNO₂ |
| Molecular Weight | 177.98 g/mol |
| Synonyms | N-Bromosuccinimide (NBS); 1-Bromo-2,5-pyrrolidinedione; Succinimide, N-bromo-; Bromosuccinimide; N-Bromo succinimide; NSC 2027; N-Bromosuccinimide (technical grade); NBS Reagent |
| EINECS | 222-479-5 |
Quality Control
Our 1-Bromopyrrolidine-2,5-Dione is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including assay (purity), identification, and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed HPLC or titration data are provided for full traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and strong oxidizing nature, keep the container tightly sealed to exclude moisture and store separately from reducing agents, acids, and organic materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Melting Point | 173 - 178 °C |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals (as Pb) | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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