Description

Aspergillomarasmine A is a potent, naturally occurring dipeptide metabolite produced by certain Aspergillus species. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a specific inhibitor of metallo-β-lactamase (MBL) enzymes, which are key contributors to bacterial antibiotic resistance. It serves as a critical research tool for scientists and developers in the fields of microbiology, enzymology, and novel antibiotic discovery, providing a pathway to combat multidrug-resistant bacterial strains.

Application

• Biochemical Research: Used as a specific inhibitor to study the structure, function, and mechanism of metallo-β-lactamase (MBL) enzymes.
• Antibiotic Resistance Research: A key tool in developing strategies and screening for novel compounds to overcome β-lactam antibiotic resistance in bacteria.
• Microbiological Studies: Employed in assays to evaluate the efficacy of antibiotic combinations against MBL-producing bacterial pathogens.
• Enzyme Inhibition Studies: Serves as a reference standard in kinetic and binding studies to understand enzyme-inhibitor interactions.
• Pharmaceutical Development: Used in early-stage research for developing new therapeutic agents that target bacterial resistance mechanisms.
• Academic Research: Utilized in university and institutional labs for fundamental research on microbial secondary metabolites and their biological activities.

Basic Information

Product Name	Aspergillomarasmine A
CAS No.	3484-65-9
Molecular Formula	C9H14N4O7
Molecular Weight	290.23 g/mol
Synonyms	Aspergillomarasmine; L-α-Amino-β-(5-amino-5-carboxy-2-oxopentylideneamino)propionic Acid; AMA; (2S)-2-Amino-3-[[(1Z)-5-amino-1-carboxy-4-oxopentylidene]amino]propanoic Acid; Aspergillomarasmin A; NSC 163049
EINECS	Contact for details

Quality Control

Our Aspergillomarasmine A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Microbial Limits	Meets standard for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.