Description

(4-Fluorobenzyl)Triphenylphosphonium Chloride is a high-value organophosphorus salt widely utilized as a key reagent in organic synthesis. Its primary value lies in its role as a stable ylide precursor for the Wittig reaction, enabling the efficient synthesis of alkenes with high stereoselectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the construction of complex molecular architectures containing fluorinated aromatic systems.

Application

• Wittig Olefination Reagent: A crucial precursor for generating stabilized ylides to synthesize fluorinated styrene derivatives and other alkenes.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) and drug candidates containing a 4-fluorobenzyl moiety.
• Agrochemical Manufacturing: Employed in the synthesis of novel herbicides, fungicides, and pesticides with fluorinated aromatic components.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated organic semiconductors and advanced display materials.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the development of specialty polymers with tailored properties.
• Cross-Coupling Reaction Catalyst/Precursor: Can be utilized in palladium-catalyzed coupling reactions to introduce fluorobenzyl groups.

Basic Information

Product Name	(4-Fluorobenzyl)Triphenylphosphonium Chloride
CAS No.	3462-95-1
Molecular Formula	C25H21ClFP
Molecular Weight	421.86 g/mol
Synonyms	4-Fluorobenzyltriphenylphosphonium Chloride; (p-Fluorobenzyl)triphenylphosphonium Chloride; [(4-Fluorophenyl)methyl]triphenylphosphonium Chloride; α-(4-Fluorophenyl)methyltriphenylphosphonium Chloride; Triphenyl(4-fluorobenzyl)phosphonium Chloride; (4-Fluorobenzyl)triphenylphosphonium Chloride; Phosphonium, (4-fluorobenzyl)triphenyl-, chloride; F-BnTPP Cl
EINECS	222-399-8

Quality Control

Our (4-Fluorobenzyl)Triphenylphosphonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	258 - 262 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.