Description

N,n-Diethyl-4-Methyl-1,3,2-Dioxaphospholan-2-Amine is a specialized organophosphorus compound, specifically a cyclic phosphoramidite, with the CAS number 3440-92-4. This chemical is a crucial intermediate and ligand in advanced organic synthesis and catalysis, valued for its ability to facilitate challenging bond-forming reactions. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Catalyst Ligand: Acts as a ligand in transition metal catalysis, enabling efficient cross-coupling and asymmetric synthesis reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Nucleoside & Nucleotide Chemistry: Employed in the synthesis and modification of nucleosides, nucleotides, and related analogs for biochemical research.
• Polymer Chemistry: Functions as a monomer or modifying agent in the synthesis of specialty polymers with tailored properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and organophosphorus chemistry.

Basic Information

Product Name	N,n-Diethyl-4-Methyl-1,3,2-Dioxaphospholan-2-Amine
CAS No.	3440-92-4
Molecular Formula	C8H18NO2P
Molecular Weight	191.21 g/mol
Synonyms	4-Methyl-2-(diethylamino)-1,3,2-dioxaphospholane; 2-(Diethylamino)-4-methyl-1,3,2-dioxaphospholane; Diethyl (4-methyl-1,3,2-dioxaphospholan-2-yl)amine; N,N-Diethyl-4-methyl-1,3,2-dioxaphospholan-2-amine; Cyclic N,N-diethylphosphoramidite of 2-methyl-1,3-propanediol; 2-Methylpropane-1,3-diyl diethylphosphoramidite
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-4-Methyl-1,3,2-Dioxaphospholan-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.