Description

2-Iodothiophene is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling critical cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the thiophene moiety contributes to biological activity.
• Material Science: Serves as a building block for conjugated polymers, organic semiconductors, and liquid crystals for electronic and optoelectronic devices.
• Chemical Research: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways in heterocyclic chemistry.
• Ligand and Catalyst Preparation: Utilized for the synthesis of specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of complex fine chemicals and specialty compounds.

Basic Information

Product Name	2-Iodothiophene
CAS No.	3437-95-4
Molecular Formula	C4H3IS
Molecular Weight	210.04 g/mol
Synonyms	Thiophene, 2-iodo-; 2-Iodothiophene; Iodothiophene; 2-Thienyl iodide; α-Iodothiophene; 2-Thiophene iodide; 2-Iodo-thiophene; 2-Thienyl iodine
EINECS	222-350-5

Quality Control

Our 2-Iodothiophene is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports traceability and meets the stringent requirements of cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its sensitivity to light and organic solvents, the container should be kept in the original packaging until use. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.