Description

2-(Bromomethyl)-2-Phenyl-1,3-Dioxolane is a versatile brominated acetal building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, where the bromomethyl group serves as an excellent electrophile for alkylation, while the protected carbonyl moiety offers a latent aldehyde functionality. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing phenylacetaldehyde units in a protected form.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that require specific phenyl-containing side chains.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel phosphine or nitrogen-based ligands used in asymmetric catalysis.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Fine Chemical Production: Employed in multi-step syntheses of fragrances, flavors, and advanced electronic chemicals.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry, including studies on nucleophilic substitution and protecting group strategies.

Basic Information

Product Name	2-(Bromomethyl)-2-Phenyl-1,3-Dioxolane
CAS No.	3418-21-1
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	α-Bromo-2-phenyl-1,3-dioxolane-2-ethanol; 2-Phenyl-2-(bromomethyl)-1,3-dioxolane; (2-Bromo-1,3-dioxolan-2-ylmethyl)benzene; Phenylacetaldehyde ethylene acetal bromomethyl; Bromomethyl phenyl dioxolane; 1,3-Dioxolane, 2-(bromomethyl)-2-phenyl-; Bromo(phenylacetaldehyde ethylene acetal)methane
EINECS	222-317-6

Quality Control

Our 2-(Bromomethyl)-2-Phenyl-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in cGMP-compliant synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.530 - 1.540
Density (20°C)	1.40 - 1.50 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.