Description

5-Phenyl-4H-1,2,4-Triazole-3-Thiol is a versatile heterocyclic organic compound featuring a triazole core substituted with a phenyl group and a thiol moiety. This structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily sought by research institutions, pharmaceutical developers, and fine chemical manufacturers for creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including potential antiviral, antifungal, and anti-inflammatory agents.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Coordination Chemistry & Material Science: Acts as a ligand for metal complexes due to its thiol and nitrogen donor atoms, useful in catalysis and advanced material design.
• Corrosion Inhibitor Precursor: Serves as a starting material for synthesizing specialized compounds used to protect metals in industrial processes.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	5-Phenyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	3414-94-6
Molecular Formula	C8H7N3S
Molecular Weight	177.23 g/mol
Synonyms	3-Mercapto-5-phenyl-1,2,4-triazole; 5-Phenyl-1H-1,2,4-triazole-3-thiol; 5-Phenyl-3-mercapto-1,2,4-triazole; 3-Phenyl-5-thiol-1,2,4-triazole; 1,2,4-Triazole-3-thiol, 5-phenyl-; 5-Phenyl-4H-1,2,4-triazole-3-thione (tautomer); NSC 403697
EINECS	222-311-8

Quality Control

Our production of 5-Phenyl-4H-1,2,4-Triazole-3-Thiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using modern analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation and moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	248 - 252 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.