Description

5-Nitro-3-[[4-(Phenylmethyl)-1-Piperazinyl]Methyl]-1H-Indole is a specialized heterocyclic organic compound featuring a nitro-substituted indole core linked to a benzylpiperazine moiety. This unique molecular architecture makes it a valuable intermediate for pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought by research institutions and chemical manufacturers engaged in medicinal chemistry, serving as a key building block for potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with potential psychotropic or neurological activity.
• Medicinal Chemistry Research: Used as a core scaffold or building block in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Employed in the development of receptor ligands and enzyme inhibitors for investigative and diagnostic purposes.
• Contract Research Organization (CRO) Supply: Supplied to CROs and academic labs for custom synthesis and proprietary research projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in related chemical processes.

Basic Information

Product Name	5-Nitro-3-[[4-(Phenylmethyl)-1-Piperazinyl]Methyl]-1H-Indole
CAS No.	3414-72-0
Molecular Formula	C20H22N4O2
Molecular Weight	350.42 g/mol
Synonyms	5-Nitro-3-[(4-benzylpiperazin-1-yl)methyl]-1H-indole; 3-[(4-Benzylpiperazin-1-yl)methyl]-5-nitro-1H-indole; 1H-Indole, 5-nitro-3-[[4-(phenylmethyl)-1-piperazinyl]methyl]-; 5-Nitro-3-((4-benzylpiperazin-1-yl)methyl)-1H-indole; 3414-72-0; 5-Nitro-3-(4-benzylpiperazinomethyl)indole
EINECS	Contact for details

Quality Control

Our 5-Nitro-3-[[4-(Phenylmethyl)-1-Piperazinyl]Methyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.