Description

5-Nitro-3-(Pyrrolidin-1-Ylmethyl)-1H-Indole is a high-value, synthetically versatile heterocyclic building block. This compound is critical for research and development in advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable indole and nitro functional groups.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds, including fused ring systems and novel chemical libraries for screening.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and pesticides.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers.

Basic Information

Product Name	5-Nitro-3-(Pyrrolidin-1-Ylmethyl)-1H-Indole
CAS No.	3414-68-4
Molecular Formula	C₁₄H₁₇N₃O₂
Molecular Weight	259.31 g/mol
Synonyms	1H-Indole, 5-nitro-3-(1-pyrrolidinylmethyl)-; 3-(Pyrrolidin-1-ylmethyl)-5-nitro-1H-indole; 5-Nitro-3-(pyrrolidin-1-ylmethyl)indole; 5-Nitro-3-pyrrolidin-1-ylmethyl-1H-indole; 3414-68-4; 5-Nitro-3-(1-pyrrolidinylmethyl)indole
EINECS	Contact for details

Quality Control

Our production of 5-Nitro-3-(Pyrrolidin-1-Ylmethyl)-1H-Indole adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.