Description

2-Ethyl-2,3,4,4A,6,11,12,12A-Octahydro-12A-Hydroxy-12-Methylpyrido[3',4':5,6]Cyclohept[1,2-B]Indole-5,5(1H)-Dimethanol is a complex, high-purity organic compound with a polycyclic indole alkaloid-like structure, serving as a critical advanced intermediate in pharmaceutical synthesis. Its intricate molecular framework makes it an essential building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system. This compound is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Process Development & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material and commercial manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control, method development, and regulatory submissions.
• Biochemical Research: Investigated for its potential biological activity and interactions in various in vitro and in vivo studies.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized, high-value organic compounds for various industrial applications.

Basic Information

Product Name	2-Ethyl-2,3,4,4A,6,11,12,12A-Octahydro-12A-Hydroxy-12-Methylpyrido[3',4':5,6]Cyclohept[1,2-B]Indole-5,5(1H)-Dimethanol
CAS No.	3368-88-5
Molecular Formula	C22H30N2O3
Molecular Weight	370.49 g/mol
Synonyms	5,5-Bis(hydroxymethyl)-2-ethyl-12a-hydroxy-12-methyl-2,3,4,4a,6,11,12,12a-octahydro-1H-pyrido[3',4':5,6]cyclohepta[1,2-b]indole; Deserpidine Impurity; 11-Desmethoxyreserpine; Canescine Impurity; Raunormine Impurity; (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester derivative; Reserpine Analog Intermediate
EINECS	Contact for details

Quality Control

Our 2-Ethyl-2,3,4,4A,6,11,12,12A-Octahydro-12A-Hydroxy-12-Methylpyrido[3',4':5,6]Cyclohept[1,2-B]Indole-5,5(1H)-Dimethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods including HPLC, GC, and NMR. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.