Description

4-(Chloromethyl)Thiazole is a versatile and reactive heterocyclic building block essential for advanced organic synthesis. Its bifunctional nature, featuring both a reactive chloromethyl group and an electron-rich thiazole ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with thiazole-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and insecticides where the thiazole moiety imparts biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic pathways.

Basic Information

Product Name	4-(Chloromethyl)Thiazole
CAS No.	3364-76-9
Molecular Formula	C4H4ClNS
Molecular Weight	133.60 g/mol
Synonyms	4-(Chloromethyl)-1,3-thiazole; Thiazole, 4-(chloromethyl)-; 4-Chloromethylthiazole; 4-Thiazolylmethyl chloride; 3364-76-9; 4-(Chloromethyl)-thiazole; 4-(Chloromethyl)thiazole
EINECS	222-157-8

Quality Control

Our 4-(Chloromethyl)Thiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring the material is suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.