Description

2-Acetyl-2,3,4,4A,5,6,11,12-Octahydro-5-(Hydroxymethyl)-12-Methyl-1H-12A,5-(Epoxymethano)Pyrido[3',4':5,6]Cyclohept[1,2-B]Indol-14-One is a complex heterocyclic organic compound featuring a fused polycyclic structure with acetyl, hydroxymethyl, and epoxymethano functional groups. This compound serves as a highly valuable advanced intermediate in the synthesis of complex pharmacologically active molecules, particularly in alkaloid chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for developing new therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex indole and pyrroloindole alkaloids with potential biological activity.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates targeting central nervous system (CNS) disorders, oncology, or infectious diseases.
• Organic Synthesis Reference Standard: Serves as a pure standard for analytical method development and validation in QC laboratories.
• Academic & Institutional Research: Utilized in universities and research institutes for studying complex heterocyclic reaction mechanisms and natural product synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) during process optimization stages.

Basic Information

Product Name	2-Acetyl-2,3,4,4A,5,6,11,12-Octahydro-5-(Hydroxymethyl)-12-Methyl-1H-12A,5-(Epoxymethano)Pyrido[3',4':5,6]Cyclohept[1,2-B]Indol-14-One
CAS No.	3329-92-8
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	2-Acetyl-2,3,4,4a,5,6,11,12-octahydro-5-(hydroxymethyl)-12-methyl-1H-12a,5-(epoxymethano)pyrido[3',4':5,6]cyclohept[1,2-b]indol-14-one; 12a,5-Epoxymethano-2-acetyl-5-hydroxymethyl-12-methyl-2,3,4,4a,5,6,11,12-octahydro-1H-pyrido[3',4':5,6]cyclohept[1,2-b]indol-14-one; 2-Acetyl-5-(hydroxymethyl)-12-methyl-12a,5-epoxymethano-2,3,4,4a,5,6,11,12-octahydro-1H-pyrido[3',4':5,6]cyclohept[1,2-b]indol-14-one; A complex pyrroloindole derivative.
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatographic data and spectral profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.