Description

7,8-Didehydro-3-Methoxy-17-Methylmorphinan-6α-Ol CAS NO 3205-45-6 is a high-purity synthetic opioid alkaloid derivative, structurally related to morphine. This compound is of significant value as a critical intermediate in advanced pharmaceutical research and development, particularly for the synthesis of specialized analgesics and for receptor binding studies. It is primarily required by pharmaceutical R&D laboratories, analytical reference standard producers, and fine chemical manufacturers engaged in the development of controlled substance analogs and neuropharmacological agents.

Application

• Pharmaceutical Intermediate: A key building block in the research-scale synthesis of potent opioid analgesics and their derivatives.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of related substances.
• Biochemical Research: Employed in neuroscience and pharmacology research to study opioid receptor binding, affinity, and functional activity.
• Forensic Analysis: Serves as an analytical standard for the identification and quantification of controlled substances in forensic toxicology.
• Metabolite Studies: Utilized in the study of drug metabolism and pharmacokinetics (DMPK) for related pharmaceutical compounds.
• Process Chemistry: Acts as a precursor in the development and optimization of synthetic routes for complex morphinan-based molecules.

Basic Information

Product Name	7,8-Didehydro-3-Methoxy-17-Methylmorphinan-6α-Ol
CAS No.	3205-45-6
Molecular Formula	C₁₉H₂₃NO₂
Molecular Weight	297.39 g/mol
Synonyms	6α-Hydroxy-3-methoxy-17-methyl-7,8-didehydromorphinan; 3-O-Methyl-6α-hydroxymorphinan; 6α-Hydroxy-3-O-methylmorphinan; 3-Methoxy-6α-hydroxymorphinan; 17-Methyl-6α-hydroxy-3-methoxy-7,8-didehydromorphinan; Morphinan-6α-ol, 7,8-didehydro-3-methoxy-17-methyl-; A key intermediate for opioid analogs.
EINECS	Contact for details

Quality Control

Our 7,8-Didehydro-3-Methoxy-17-Methylmorphinan-6α-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.