Description

6,7-Dimethoxy-1-Pyridin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used extensively in R&D laboratories for structure-activity relationship (SAR) studies and lead optimization processes.
• Active Pharmaceutical Ingredient (API) Synthesis: A key starting material or intermediate in the production pathway of specific, proprietary APIs.
• Biochemical Tool Compound: Employed in biochemical assays and pharmacological studies to investigate specific biological pathways and mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	6,7-Dimethoxy-1-Pyridin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	3161-05-5
Molecular Formula	C₁₆H₁₈N₂O₂
Molecular Weight	270.33 g/mol
Synonyms	1-(4-Pyridinyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-(4-pyridinyl)-1,2,3,4-tetrahydroisoquinoline; 1-(Pyridin-4-yl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl)pyridine; NSC 403914; Tetrahydroisoquinoline derivative, 6,7-dimethoxy-1-(4-pyridyl)-; 3161-05-5
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-Pyridin-4-Yl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.