Description

n-Dodecylboronic Acid is a high-purity, long-chain alkylboronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize complex organic molecules, liquid crystals, and functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and alkyl-aryl motifs present in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by introducing the dodecyl chain to modulate lipophilicity and bioactivity.
• Material Science: Serves as a monomer or modifier in the synthesis of organic semiconductors, liquid crystals, and self-assembled monolayers (SAMs) for electronic devices.
• Polymer Chemistry: Acts as a chain-transfer agent or functional initiator in controlled radical polymerizations to create polymers with tailored end-group functionality.
• Organic Synthesis: Employed in petide coupling and as a protecting group for diols in complex multi-step synthetic routes.
• Catalyst & Ligand Development: Utilized to create novel boron-containing ligands for transition metal catalysis.

Basic Information

Product Name	n-Dodecylboronic Acid
CAS No.	3088-79-7
Molecular Formula	C₁₂H₂₇BO₂
Molecular Weight	214.16 g/mol
Synonyms	Dodecylboronic Acid; Laurylboronic Acid; 1-Dodecylboronic Acid; n-Laurylboronic Acid; Boronic acid, dodecyl-; Dodecaneboronic Acid; Lauryl Boric Acid; B-Dodecylboronic Acid
EINECS	221-415-4

Quality Control

Our n-Dodecylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets stringent specifications for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.