Description

[R-(R*,S*)]-3,7-Dihydro-7-[2-[(2-Hydroxy-1-Methyl-2-Phenylethyl)Amino]Ethyl]-1,3-Dimethyl-1H-Purine-2,6-Dione Monohydrochloride is a high-purity, pharmacologically active compound primarily used as a key intermediate in advanced pharmaceutical synthesis. Its value lies in its specific stereochemistry and functional groups, which are critical for producing targeted therapeutic agents. This product is essential for research institutions and manufacturers in the pharmaceutical industry, particularly those developing or producing cardiovascular and respiratory medications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially xanthine derivatives.
• Cardiovascular Research: Used in the development and production of compounds targeting adenosine receptors for cardiovascular applications.
• Respiratory Drug Development: Serves as a precursor for bronchodilator medications.
• Biochemical Research: Employed in pharmacological studies and as a reference standard in analytical laboratories.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for drug candidates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.

Basic Information

Product Name	[R-(R*,S*)]-3,7-Dihydro-7-[2-[(2-Hydroxy-1-Methyl-2-Phenylethyl)Amino]Ethyl]-1,3-Dimethyl-1H-Purine-2,6-Dione Monohydrochloride
CAS No.	3039-97-2
Molecular Formula	C19H26N6O3 • HCl
Molecular Weight	422.91 g/mol
Synonyms	1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-, monohydrochloride, (R-(R*,S*))-; 7-[2-[(2-Hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione hydrochloride; Denopamine Impurity; Denopamine Related Compound; (R,R/S)-Denopamine Hydrochloride; (R*,S*)-Denopamine HCl; 1,3-Dimethyl-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]xanthine Hydrochloride
EINECS	Contact for details

Quality Control

Our [R-(R*,S*)]-3,7-Dihydro-7-[2-[(2-Hydroxy-1-Methyl-2-Phenylethyl)Amino]Ethyl]-1,3-Dimethyl-1H-Purine-2,6-Dione Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with stringent standards for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.