Description

2-Bromothiazole is a versatile and highly reactive heterocyclic building block essential for advanced organic synthesis. Its value lies in the strategic introduction of the bromine atom, which enables efficient cross-coupling reactions and further functionalization. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiazole ring's bioactivity.
• Material Science Research: Serves as a monomer or building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings to form carbon-carbon bonds, facilitating the construction of complex molecules.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Used to synthesize labeled compounds or probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	2-Bromothiazole
CAS No.	3034-53-5
Molecular Formula	C3H2BrNS
Molecular Weight	163.99 g/mol
Synonyms	2-Bromo-1,3-thiazole; Thiazole, 2-bromo-; 2-Bromothiazole; 2-Thiazolyl bromide; Bromothiazole; NSC 403697; AI3-52711; CCRIS 6665
EINECS	221-231-5

Quality Control

Every batch of our 2-Bromothiazole is produced and tested under a strict quality management system. We guarantee high-purity material suitable for demanding synthetic applications, with comprehensive testing including HPLC for assay and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with our rigorous in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and away from heat and ignition sources. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.8 g/cm³
Boiling Point	~150-152 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.