Description

4,4',4''-Trichlorotrityl Alcohol is a specialized trityl-protecting group reagent featuring three chlorine substituents. This compound matters for its enhanced stability and selectivity in complex organic synthesis, particularly for the protection of hydroxyl groups under acidic conditions. It is a critical intermediate needed by pharmaceutical R&D laboratories and fine chemical manufacturers developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Protecting Group Reagent in the synthesis of nucleosides, nucleotides, and oligonucleotides.
• Key Intermediate for the preparation of solid-phase synthesis resins and functionalized polymers.
• Pharmaceutical Intermediate in the multi-step synthesis of complex drug molecules and APIs.
• Research Chemical for academic and industrial research in organic and medicinal chemistry.
• Precursor for the synthesis of other functionalized trityl derivatives and specialty chemicals.

Basic Information

Product Name	4,4',4''-Trichlorotrityl Alcohol
CAS No.	3010-80-8
Molecular Formula	C19H13Cl3O
Molecular Weight	363.66 g/mol
Synonyms	Tris(4-chlorophenyl)methanol; 4,4',4''-Trichlorotriphenylmethanol; (4-Chlorophenyl)diphenylmethanol; Tris(p-chlorophenyl)methanol; Trityl alcohol, 4,4',4''-trichloro-; α,α,α-Tris(4-chlorophenyl)methanol; NSC 403697; Tris(4-chlorophenyl)carbinol
EINECS	221-138-7

Quality Control

Our 4,4',4''-Trichlorotrityl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.