Description

3-Fluoroisoquinoline is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom onto the isoquinoline scaffold, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and other electronic materials.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and studying structure-activity relationships (SAR).
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Fluoroisoquinoline
CAS No.	396-29-2
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	Isoquinoline, 3-fluoro-; 3-Fluoro-isoquinoline; 3-Fluoroisoquinoline; 396-29-2; 3-Fluoro-1-azanaphthalene; 3-Fluoro-1-azaanthracene (obsolete); NSC 406908; AI3-52072
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoroisoquinoline is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.