Description

2-Bromo-3-Chlorobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzotrifluoride core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electronic chemicals used in display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties like flame retardancy or chemical resistance.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions for creating biaryl structures.
• Organic Synthesis Research: A high-value reagent for academic and industrial R&D exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-3-Chlorobenzotrifluoride
CAS No.	384-16-7
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	1-Bromo-2-chloro-3-(trifluoromethyl)benzene; 3-Chloro-2-bromobenzotrifluoride; 2-Chloro-α,α,α-trifluoro-6-bromotoluene; Benzene, 1-bromo-2-chloro-3-(trifluoromethyl)-; 2-Bromo-3-chloro-α,α,α-trifluorotoluene; 2-Bromo-3-chloro-(trifluoromethyl)benzene; 3-Chloro-2-bromo-α,α,α-trifluorotoluene
EINECS	206-846-5

Quality Control

Our 2-Bromo-3-Chlorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical process development and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.75 g/cm³
Refractive Index (n20D)	~1.48

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.