Description

2-(Pentafluoroethyl)Benzimidazole is a specialized fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a benzimidazole core with a pentafluoroethyl substituent, provides valuable properties for creating high-performance materials and active pharmaceutical ingredients. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorine for enhanced metabolic stability, lipophilicity, and biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis and material science applications.
• Functional Material Research: Intermediate for synthesizing fluorinated polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent tags and molecular probes used in diagnostic and research applications.
• Custom Synthesis & R&D: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	2-(Pentafluoroethyl)Benzimidazole
CAS No.	383-08-4
Molecular Formula	C9H5F5N2
Molecular Weight	236.14 g/mol
Synonyms	2-(Pentafluoroethyl)-1H-benzimidazole; 1H-Benzimidazole, 2-(pentafluoroethyl)-; 2-(Pentafluoroethyl)-1H-benzo[d]imidazole; Benzimidazole, 2-(pentafluoroethyl)-; 383-08-4; Pentafluoroethylbenzimidazole; 2-Pentafluoroethylbenzimidazole
EINECS	Contact for details

Quality Control

Our 2-(Pentafluoroethyl)Benzimidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. For projects requiring specific regulatory support, we can supply material with documentation aligned with cGMP and ICH Q7 guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.